SYT2 antibody (N-Term)

Catalog No. ABIN350917

This Sheep Polyclonal antibody specifically detects SYT2 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for SYT2 antibody (N-Term) (ABIN350917)

Target: SYT2 (Synaptotagmin II (SYT2))

Reactivity: Human

Host: Sheep

Clonality: Polyclonal

Conjugate: This SYT2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SYT2 Antibody

Binding Specificity: N-Term

Purpose: Sheep antibody to Synaptotagmin2

Specificity: Specific for SYTII.

Cross-Reactivity: Human, Mouse, Rat

Cross-Reactivity (Details): Other species not yet tested.

Purification: IgG

Immunogen: A synthetic peptide from the n-terminal region of human Synaptotagmin-2 (Synaptotagmin II SytII SYT2) conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and mouse.

Isotype: IgG

Application Details

Application Notes: IHC WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.

Handling Advice: Avoid freeze and thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date: 12 months

Target Details for SYT2

Target: SYT2 (Synaptotagmin II (SYT2))

Alternative Name: Synaptotagmin2

Background: Synaptotagmins like SYT2 are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. FUNCTION: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. SUBUNIT: Homotetramer. Interacts with stonin 2. SUBCELLULAR LOCATION: Cytoplasmic vesicle secretory vesicle synaptic vesicle. Cytoplasmic vesicle secretory vesicle chromaffin granule. Note: Synaptic vesicles and chromaffin granules.

UniProt: Q8N9I0

Pathways: Synaptic Vesicle Exocytosis