STXB1 antibody (AA 460-510)

Catalog No. ABIN350945

The Rabbit Polyclonal anti-STXB1 antibody has been validated for WB and IHC. It is suitable to detect STXB1 in samples from Human.

Quick Overview for STXB1 antibody (AA 460-510) (ABIN350945)

Target: STXB1 (Stx1B) (Shiga Toxin 1 Subunit B (Stx1B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STXB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-STXB1 Antibody

Binding Specificity: AA 460-510

Purpose: Rabbit antibody to STXB1 (460-510)

Specificity: Specific for Syntaxin-binding protein 1.

Cross-Reactivity: Human, Mouse, Rat

Cross-Reactivity (Details): Other species not yet tested.

Purification: IgG

Immunogen: A synthetic peptide from AA 460-510 of human STXB1 conjugated to blue carrier protein was used as the antigen. The peptide is homologous with the corresponding sequence in rat mouse chicken and monkey.

Isotype: IgG

Application Details

Application Notes: IHC WB. A concentration of 0.1 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.

Handling Advice: Avoid freeze and thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date: 12 months

Target Details for STXB1

Target: STXB1 (Stx1B) (Shiga Toxin 1 Subunit B (Stx1B))

Alternative Name: STXB1

Background: FUNCTION: May participate in the regulation of synaptic vesicle docking and fusion possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1 2 and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions.

UniProt: P61764