Thyroglobulin antibody

Catalog No. ABIN351006

Product Details anti-Thyroglobulin Antibody

Target: Thyroglobulin (TG)

Reactivity: Mouse

Host: Sheep

Clonality: Polyclonal

Conjugate: This Thyroglobulin antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Specificity: Specific for TGN38.

Cross-Reactivity: Human, Marmoset, Mouse, Rat

Cross-Reactivity (Details): Other species not yet tested.

Purification: IgG

Immunogen: A synthetic peptide from mouse TGN38 conjugated to blue carrier protein was used as the antigen.

Isotype: IgG

Application Details

Application Notes: IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.

Handling Advice: Avoid freeze and thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date: 12 months

Target Details for Thyroglobulin

Target: Thyroglobulin (TG)

Alternative Name: TGN (TG Products)

Background: FUNCTION: May be involved in regulating membrane traffic to and from trans-Golgi network. SUBCELLULAR LOCATION: Cell membrane, Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane, Single-pass type I membrane protein. Note: Primarily in trans-Golgi network. Cycles between the trans-Golgi network and the cell surface returning via endosomes. TISSUE SPECIFICITY: Isoform TGN46 is widely expressed. Isoform TGN51 is more abundant in fetal lung and kidney. Isoform TGN48 is barely expressed in embryonic kidney and promyelocytic cells. MISCELLANEOUS: Not found in strains BALB/c, C57BL/6 and DBA/2.,Subcellular Markers,Trans-Golgi network protein TGN51, TGN46, TGN48, TGN38 homolog, Trans-Golgi network integral membrane protein 2, TGOLN2

UniProt: O43493

Pathways: Thyroid Hormone Synthesis