SEC22B antibody (AA 2-50)

Catalog No. ABIN351370

This Rabbit Polyclonal antibody specifically detects SEC22B in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for SEC22B antibody (AA 2-50) (ABIN351370)

Target: SEC22B (SEC22b Vesicle Trafficking Protein (SEC22B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEC22B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SEC22B Antibody

Binding Specificity: AA 2-50

Purpose: Rabbit antibody to SEC22B (2-50)

Specificity: Specific for SEC22B.

Cross-Reactivity: Human, Mouse, Rat

Cross-Reactivity (Details): Other species not yet tested.

Purification: IgG

Immunogen: A synthetic peptide from AA 2-50 of human SEC22b conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and mouse.

Isotype: IgG

Application Details

Application Notes: IHC WB. A working concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.

Handling Advice: Avoid freeze and thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date: 12 months

Target Details for SEC22B

Target: SEC22B (SEC22b Vesicle Trafficking Protein (SEC22B))

Alternative Name: SEC22B

Background: FUNCTION: SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER. SUBUNIT: Component of two distinct SNARE complexes consisting of STX5 GOSR2/BOS1 BET1 and SEC22B or STX18 USE1L BNIP1/SEC20L and SEC22B. YKT6 can probably replace SEC22B in either complex. SUBCELLULAR LOCATION: Endoplasmic reticulum-Golgi intermediate compartment membrane, Single-pass type IV membrane protein. Golgi apparatus membrane, Single-pass type IV membrane protein. Melanosome.

UniProt: O75396