PERP antibody (C-Term)

Catalog No. ABIN356105

The Rabbit Polyclonal anti-PERP antibody has been validated for WB and IHC. It is suitable to detect PERP in samples from Human.

Quick Overview for PERP antibody (C-Term) (ABIN356105)

Target: PERP (TP53 Apoptosis Effector (PERP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PERP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PERP Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human

Purification: affinity purified

Immunogen: Synthetic peptide corresponding to AA near the carboxy terminus of human PERP, which differ from the mouse sequence by three AA (7-9).

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: -20 °C

Target Details for PERP

Target: PERP (TP53 Apoptosis Effector (PERP))

Alternative Name: PERP/TP53 Apoptosis Effector Protein

Background: The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. PERP (TP53 Apoptosis Effector) is a plasma membrane protein. p53 binds to the promoter of PERP and transcriptionally activates PERP gene then the translated PERP protein mediates the p53 induced apoptosis. The expression of PERP causes cell death. PERP is a mediator of p53 induced apoptosis. PERP has sequence similarity to PMP-22/gas3 and is a new member of the PMP-22/gas3 family.

Pathways: Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity