LYZ antibody

Catalog No. ABIN356481

The Rabbit Polyclonal anti-LYZ antibody (ABIN356481) specifically detects LYZ in IF, IHC (p) and IHC (fro). The antibody is reactive with Human samples.

Quick Overview for LYZ antibody (ABIN356481)

Target: LYZ (Lysozyme (LYZ))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LYZ antibody is un-conjugated

Application: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-LYZ Antibody

Specificity: This antibody labels myeloid cells, histocytes, granulocytes, macrophages and monocyes. It is helpful in detection of myeloid or monocytic nature of acute leukemia.
Cellular Localization: Cytoplasmic.

Purification: Purified

Immunogen: Purified human Lysozyme from the urine of patients with monocytic leukemia.

Isotype: IgG

Application Details

Application Notes: Suitable for Immunohistochemistry and Immunocytochemistry (Frozen or Formalin-FixedParaffin-Embedded (FFPE) tissue sections and cell smears): 1/50-1/100 usingstreptavidinapprox. biotin system or polymer system. Recommended positive control: Human tonsil.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 2.0 mg/mL

Buffer: PBS, pH 7.4 containing 0.05 % Sodium Azide as preservative and 1 % BSA as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for LYZ

Target: LYZ (Lysozyme (LYZ))

Alternative Name: Lysozyme C

Background: Lysozyme is 129 amino acids, 14.4 kDa enzyme that hydrolyzes 1,4 beta linkage between N-acetylmuramic acid and N-acetyl glucosamine residue in peptiglycan and between N-acetyl glucosamine's residues in chitodextrins. It is found in secretions, tears, saliva and mucus. It is also found in Cytoplasmic granules of the polymorphonuclear neutrophils (PMN) and egg whites. It has also been reported in spleen, kidney, lung, WBC and plasma.Synonyms: 1, 4-beta-N-acetylmuramidase C, LYZ, LZM

Gene ID: 4069

NCBI Accession: NP_000230

UniProt: P61626