HAT1 antibody (C-Term)

Catalog No. ABIN356621

The Rabbit Polyclonal anti-HAT1 antibody has been validated for WB and EIA. It is suitable to detect HAT1 in samples from Human.

Quick Overview for HAT1 antibody (C-Term) (ABIN356621)

Target: HAT1 (Histone Acetyltransferase 1 (HAT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HAT1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-HAT1 Antibody

Binding Specificity: AA 390-419, C-Term

Specificity: This antibody is specific to Human HAT1 (C-term).

Purification: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: KLH conjugated synthetic peptide between 390~419 amino acids from the C-terminal region of Human HAT1

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for HAT1

Target: HAT1 (Histone Acetyltransferase 1 (HAT1))

Alternative Name: HAT1

Background: Histone acetylation, particularly of histone H4, has been proposed to play an important role in replication-dependent nucleosome assembly. The HAT1 protein contains D, A, and B motifs, which are present in many N-acetyltransferases, including those that acetylate substrates other than histones. The HAT1 holoenzyme consists of 2 subunits: the catalytic 46-kD HAT1 and the accessory p46. The p46 subunit stimulated the activity of HAT1 and bound to core histones. The HAT1 holoenzyme acetylated newly synthesized but not nucleosomal histone H4 at lys5 and lys12, and, to a lesser extent, histone H2A at lys5. HAT1 and p46 polypeptides are located in the nucleus of S-phase cells. HAT1 may play a role in telomeric silencing.Synonyms: Histone acetyltransferase type B catalytic subunit

Gene ID: 8520, 9606

UniProt: O14929