BCL2L2 antibody (BH3 Domain, N-Term)

Catalog No. ABIN356814

This anti-BCL2L2 antibody is a Rabbit Polyclonal antibody detecting BCL2L2 in WB, IHC (p) and EIA. Suitable for Human and Mouse.

Quick Overview for BCL2L2 antibody (BH3 Domain, N-Term) (ABIN356814)

Target: BCL2L2 (BCL2-Like 2 (BCL2L2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCL2L2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-BCL2L2 Antibody

Binding Specificity: AA 1-100, BH3 Domain, N-Term

Specificity: This antibody is specific to Bcl-w (BH3 Domain).

Purification: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This antibody was developed against a synthetic peptide corresponding within amino acid residues 1-100 of human Bcl-W.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for BCL2L2

Target: BCL2L2 (BCL2-Like 2 (BCL2L2))

Alternative Name: Bcl-2-Like 2

Background: Bcl-w is a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis.Synonyms: BCL2L2, BCLW, Bcl-w, Bcl2-L-2, KIAA0271

Gene ID: 599, 9606

UniProt: Q92843