YBX2 antibody (C-Term)

Catalog No. ABIN356883

This anti-YBX2 antibody is a Rabbit Polyclonal antibody detecting YBX2 in IHC (p) and EIA. Suitable for Human.

Quick Overview for YBX2 antibody (C-Term) (ABIN356883)

Target: YBX2 (Y Box Binding Protein 2 (YBX2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YBX2 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-YBX2 Antibody

Binding Specificity: C-Term

Specificity: This antibody detects YBX2 at C-term.

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human YBX2.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA 1: 1,000. Immunohistochemistry 1: 10 - 1: 50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Target Details for YBX2

Target: YBX2 (Y Box Binding Protein 2 (YBX2))

Alternative Name: YBX2

Background: YBX2 is a major constituent of messenger ribonucleoprotein particles (mRNPs). It is nvolved in the regulation of the stability and/or translation of germ cell mRNAs. It binds to Y-box consensus promoter element and to full length mRNA with high affinity in a sequence-independent manner. It binds to short RNA sequences containing the consensus site 5'-UCCAUCA-3' with low affinity and limited sequence specificity. Its binding with maternal mRNAs is necessary for its cytoplasmic retention. YBX2 may mark specific mRNAs (those transcribed from Y-box promoters) in the nucleus for cytoplasmic storage, thereby linking transcription and mRNA storage/translational delay.Synonyms: CSDA3, Contrin, DBPC, DNA-binding protein C, Germ cell-specific Y-box-binding protein, MSY2, MSY2 homolog, Y-box-binding protein 2

Molecular Weight: 38518 Da

Gene ID: 51087, 9606

UniProt: Q9Y2T7

Pathways: Chromatin Binding