YBX2 antibody (Middle Region)

Catalog No. ABIN356884

This Rabbit Polyclonal antibody specifically detects YBX2 in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for YBX2 antibody (Middle Region) (ABIN356884)

Target: YBX2 (Y Box Binding Protein 2 (YBX2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YBX2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-YBX2 Antibody

Binding Specificity: Middle Region

Specificity: This antibody detects YBX2 at center.

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA 1: 1,000. Western blot 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Target Details for YBX2

Target: YBX2 (Y Box Binding Protein 2 (YBX2))

Alternative Name: YBX2

Background: Major constituent of messenger ribonucleoprotein particles (mRNPs). Involved in the regulation of the stability and/or translation of germ cell mRNAs. Binds to Y-box consensus promoter element. Binds to full length mRNA with high affinity in a sequence-independent manner. Binds to short RNA sequences containing the consensus site 5'-UCCAUCA-3' with low affinity and limited sequence specificity. Its binding with maternal mRNAs is necessary for its cytoplasmic retention. May mark specific mRNAs (those transcribed from Y-box promoters) in the nucleus for cytoplasmic storage, thereby linking transcription and mRNA storage/translational delay.Synonyms: CSDA3, Contrin, DBPC, DNA-binding protein C, Germ cell-specific Y-box-binding protein, MSY2, MSY2 homolog, Y-box-binding protein 2

Molecular Weight: 38518 Da

Gene ID: 51087, 9606

UniProt: Q9Y2T7

Pathways: Chromatin Binding