CD8 antibody (N-Term)
Quick Overview for CD8 antibody (N-Term) (ABIN356887)
Target
See all CD8 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 66-96, N-Term
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Specificity
- This antibody detects Human CD8A at N-term.
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Purification
- Protein A column, followed by peptide affinity purification
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Immunogen
- KLH conjugated synthetic peptide between 66~96 amino acids from the N-terminal region of Human CD8A
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Isotype
- Ig Fraction
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Application Notes
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ELISA 1: 1,000. Western blot 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- CD8
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Alternative Name
- CD8
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Background
- The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.Synonyms: CD8 alpha chain, CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2
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Molecular Weight
- 25729 Da
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Gene ID
- 925, 9606
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UniProt
- P01732
Target
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