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TSG101 antibody (N-Term)

The Rabbit Polyclonal anti-TSG101 antibody has been validated for WB, IHC (p) and EIA. It is suitable to detect TSG101 in samples from Human and Mouse.
Catalog No. ABIN357572

Quick Overview for TSG101 antibody (N-Term) (ABIN357572)

Target

See all TSG101 Antibodies
TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Reactivity

  • 77
  • 42
  • 32
  • 11
  • 10
  • 9
  • 8
  • 8
  • 6
  • 5
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
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Human, Mouse

Host

  • 67
  • 15
Rabbit

Clonality

  • 56
  • 26
Polyclonal

Conjugate

  • 57
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This TSG101 antibody is un-conjugated

Application

  • 67
  • 34
  • 30
  • 16
  • 16
  • 12
  • 8
  • 7
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • Binding Specificity

    • 9
    • 8
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Specificity

    This antibody is specific to TSG101 (N-term).

    Purification

    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

    Immunogen

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human TSG101.

    Isotype

    Ig Fraction
  • Application Notes

    ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.25 mg/mL

    Buffer

    PBS with 0.09 % (W/V) Sodium Azide as preservative.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freezing and thawing.

    Storage

    4 °C/-20 °C

    Storage Comment

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target

    TSG101 (Tumor Susceptibility Gene 101 (TSG101))

    Alternative Name

    TSG101

    Background

    TSG101 belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.Synonyms: ESCRT-I complex subunit TSG101, Tumor susceptibility gene 101 protein

    Molecular Weight

    43944 Da

    Gene ID

    7251, 5874

    UniProt

    Q99816
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