Ubiquilin 3 antibody (N-Term)

Catalog No. ABIN357613

This Rabbit Polyclonal antibody specifically detects Ubiquilin 3 in WB, IHC (p) and EIA. It exhibits reactivity toward Human.

Quick Overview for Ubiquilin 3 antibody (N-Term) (ABIN357613)

Target: Ubiquilin 3 (UBQLN3)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ubiquilin 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-Ubiquilin 3 Antibody

Binding Specificity: N-Term

Specificity: This antibody is specific to Ubiquilin-3/UBQLN3 (N-term).

Purification: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human Ubiquilin3.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for Ubiquilin 3

Target: Ubiquilin 3 (UBQLN3)

Alternative Name: Ubiquilin-3 (UBQLN3)

Background: Ubiquilin 3 shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and are thus thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. The gene is specifically expressed in the testis, and proposed to regulate cell-cycle progression during spermatogenesis.

Molecular Weight: 72729 Da

Gene ID: 50613, 9606

UniProt: Q9H347