SULT1C2 antibody (Middle Region)

Catalog No. ABIN357806

The Rabbit Polyclonal anti-SULT1C2 antibody is suitable to detect SULT1C2 in samples from Human and Mouse. It has been validated for WB and EIA.

Quick Overview for SULT1C2 antibody (Middle Region) (ABIN357806)

Target: SULT1C2 (Sulfotransferase Family, Cytosolic, 1C, Member 2 (SULT1C2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SULT1C2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-SULT1C2 Antibody

Binding Specificity: Middle Region

Specificity: This antibody detects SULT1C1 (Center).

Purification: Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from within the central region of human SULT1C1.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western Blot: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for SULT1C2

Target: SULT1C2 (Sulfotransferase Family, Cytosolic, 1C, Member 2 (SULT1C2))

Alternative Name: SULT1C2 / SULT1C1

Background: The 296-amino acid human SULTC1 protein, so named on the basis of its significant homology to a rat hepatic cytosolic sulfotranserase ST1C1, catalyzes the sulfate conjugation of many drugs, xenobiotic compounds, hormones, and neurotransmitters, and may be involved in the activation of carcinogenic hydroxylamines. This enzyme also shows activity towards p-nitrophenol and N-hydroxy-2-acetylamino-fluorene (N-OH-2AAF). SULT1C1 is expressed as a 1.4-kb mRNA in adult human stomach, kidney, and thyroid, and in fetal kidney and liver. By functional characterization of recombinant protein, it has been shown that SULT1C1 catalyzes the sulfonation of p-nitrophenol and N-hydroxy-2-acetylaminofluorene, but not dopamine, 17-beta-estradiol, or dehydroepiandrosterone.Synonyms: ST1C2, Sulfotransferase 1C1, Sulfotransferase 1C2, humSULTC2

Molecular Weight: 34880 Da

Gene ID: 6819

NCBI Accession: NP_001047

UniProt: O00338