DTNBP1 antibody (N-Term)

Catalog No. ABIN357845

The Rabbit Polyclonal anti-DTNBP1 antibody has been validated for WB, IHC (p) and EIA. It is suitable to detect DTNBP1 in samples from Human and Mouse.

Quick Overview for DTNBP1 antibody (N-Term) (ABIN357845)

Target: DTNBP1 (Dystrobrevin Binding Protein 1 (DTNBP1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DTNBP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-DTNBP1 Antibody

Binding Specificity: N-Term

Specificity: This antibody detects DTNBP1 (N-term).

Purification: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of mouse Dtnbp1.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blot: 1/50-1/100. Immunohistochemistry: 1/10-1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for DTNBP1

Target: DTNBP1 (Dystrobrevin Binding Protein 1 (DTNBP1))

Alternative Name: Dysbindin

Background: Dtnbp1 may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and binds to alpha- and beta-dystrobrevins, which are components of the dystrophin-associated protein complex (DPC). Mutations are associated with Hermansky-Pudlak syndrome type 7. This protein may also be associated with schizophrenia.Synonyms: DTNBP1, Dystrobrevin-binding protein 1, Hermansky-Pudlak syndrome 7 protein homolog, Hps7-like protein, My031

Molecular Weight: 39651 Da

Gene ID: 94245, 10090

UniProt: Q91WZ8

Pathways: Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling