Junctophilin 3 antibody (Middle Region)

Catalog No. ABIN357848

The Rabbit Polyclonal anti-Junctophilin 3 antibody has been validated for WB, IHC (p) and EIA. It is suitable to detect Junctophilin 3 in samples from Human and Mouse.

Quick Overview for Junctophilin 3 antibody (Middle Region) (ABIN357848)

Target: Junctophilin 3 (JPH3)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Junctophilin 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-Junctophilin 3 Antibody

Binding Specificity: Middle Region

Specificity: This antibody detects Junctophilin 3 (Center).

Purification: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of mouse Jph3.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western Blot: 1/50-1/100. Immunohistochemistry: 1/10-1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for Junctophilin 3

Target: Junctophilin 3 (JPH3)

Alternative Name: Junctophilin-3 / JPH3

Background: Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. Junctophilin 3 is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane.Synonyms: JP3, Junctophilin type 3, TNRC22, Trinucleotide repeat-containing gene 22 protein

Molecular Weight: 81229 Da

Gene ID: 57340, 10090

UniProt: Q9ET77