FZD1 antibody (Middle Region)

Catalog No. ABIN357911

The Rabbit Polyclonal anti-FZD1 antibody has been validated for WB, IF, FACS, IHC (p) and EIA. It is suitable to detect FZD1 in samples from Human.

Quick Overview for FZD1 antibody (Middle Region) (ABIN357911)

Target: FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FZD1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-FZD1 Antibody

Binding Specificity: AA 374-404, Middle Region

Specificity: This antibody detects FZD1 (Center). Predicted to cross react with Rat and Mouse (100 % Antigen Homology).

Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: KLH conjugated synthetic peptide between 374~404 amino acids from the center region of Human FZD1. Genename: FZD1

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western Blot: 1/50-1/100. Immunohistochemistry: 1/10-1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for FZD1

Target: FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))

Alternative Name: FZD1 / Frizzled-1

Background: Members of the 'frizzled' family are 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif.Synonyms: Fz-1, FzE1, hFz1

Molecular Weight: 71158 Da

Gene ID: 8321, 9606

UniProt: Q9UP38

Pathways: WNT Signaling, Asymmetric Protein Localization