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FOXP3 antibody (C-Term)

This Rabbit Polyclonal antibody specifically detects FOXP3 in WB, IHC (p) and EIA. It exhibits reactivity toward Human and Mouse.
Catalog No. ABIN357961

Quick Overview for FOXP3 antibody (C-Term) (ABIN357961)

Target

See all FOXP3 Antibodies
FOXP3 (Forkhead Box P3 (FOXP3))

Reactivity

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Human, Mouse

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This FOXP3 antibody is un-conjugated

Application

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • Binding Specificity

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    AA 290-319, C-Term

    Specificity

    This antibody detects FOXP3 (C-term).

    Purification

    Protein A Chromatography, followed by peptide affinity purification.

    Immunogen

    KLH conjugated synthetic peptide between 290~319 amino acids from the C-terminal region of Human FOXP3. Genename: FOXP3

    Isotype

    Ig Fraction
  • Application Notes

    ELISA: 1/1,000. Western Blot: 1/50-1/100. Immunohistochemistry: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.25 mg/mL

    Buffer

    PBS with 0.09 % (W/V) Sodium Azide as preservative.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freezing and thawing.

    Storage

    4 °C/-20 °C

    Storage Comment

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target

    FOXP3 (Forkhead Box P3 (FOXP3))

    Alternative Name

    FOXP3

    Background

    FOXP3 is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in FOXP3 gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome.Synonyms: Forkhead box protein P3, IPEX, JM2, Scurfin

    Molecular Weight

    47244 Da

    Gene ID

    50943, 9606

    UniProt

    Q9BZS1

    Pathways

    Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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