SPPL3 antibody (N-Term)

Catalog No. ABIN358855

This Rabbit Polyclonal antibody specifically detects SPPL3 in EIA. It exhibits reactivity toward Human.

Quick Overview for SPPL3 antibody (N-Term) (ABIN358855)

Target: SPPL3 (Signal Peptide Peptidase 3 (SPPL3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPPL3 antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Product Details anti-SPPL3 Antibody

Binding Specificity: N-Term

Specificity: This antibody reacts to SPPL3.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human SPPL3.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for SPPL3

Target: SPPL3 (Signal Peptide Peptidase 3 (SPPL3))

Alternative Name: SPPL3

Background: Signal peptide peptidase (SPP) is an aspartyl protease that mediates clearance of signal peptides by proteolysis within the endoplasmic reticulum (ER). Like presenilins, SPP contains a critical GXGD motif in its C-terminal catalytic center. SPPL3 is one of several presenilin homologues/SPP-like proteins (PSHs/SPPL) that have been identified.Synonyms: IMP-2, IMP2, Intramembrane protease 2, PSL4, Presenilin-like protein 4, SPP-like 3, Signal peptide peptidase-like 3

Gene ID: 121665, 9606

UniProt: Q8TCT6