Myosin IC antibody (C-Term)

Catalog No. ABIN358975

This Rabbit Polyclonal antibody specifically detects Myosin IC in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for Myosin IC antibody (C-Term) (ABIN358975)

Target: Myosin IC (MYO1C)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Myosin IC antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Myosin IC Antibody

Binding Specificity: C-Term

Specificity: This antibody reacts to Myosin 1C (MYO1C).

Purification: Protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human MYO1C.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Immunohistochemistry: 1/10 - 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for Myosin IC

Target: Myosin IC (MYO1C)

Alternative Name: Myosin-Ic

Background: MYO1C is a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane.Synonyms: MMI-beta, MMIb, MYO1C, Myosin I beta

Gene ID: 4641, 9606

UniProt: O00159

Pathways: Platelet-derived growth Factor Receptor Signaling