GCN2 antibody (C-Term)

Catalog No. ABIN359271

This anti-GCN2 antibody is a Rabbit Polyclonal antibody detecting GCN2 in WB, IHC (p) and EIA. Suitable for Human.

Quick Overview for GCN2 antibody (C-Term) (ABIN359271)

Target: GCN2 (EIF2AK4) (Eukaryotic Translation Initiation Factor 2 alpha Kinase 4 (EIF2AK4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GCN2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-GCN2 Antibody

Binding Specificity: C-Term

Specificity: This antibody reacts to GCN2.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region with glycine at position 11 of human GCN2.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western Blot: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for GCN2

Target: GCN2 (EIF2AK4) (Eukaryotic Translation Initiation Factor 2 alpha Kinase 4 (EIF2AK4))

Alternative Name: EIF2AK4 / GCN2

Background: GCN2 (EIF2AK4) belongs to a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 to downregulate protein synthesis in response to varied cellular stresses.Synonyms: Eukaryotic translation initiation factor 2-alpha kinase 4, GCN2-like protein, KIAA1338

Gene ID: 440275, 9606

UniProt: Q9P2K8

Pathways: ER-Nucleus Signaling, Hepatitis C