HMGB2 antibody (Middle Region)

Catalog No. ABIN359382

This anti-HMGB2 antibody is a Rabbit Polyclonal antibody detecting HMGB2 in WB and EIA. Suitable for Human.

Quick Overview for HMGB2 antibody (Middle Region) (ABIN359382)

Target: HMGB2 (High Mobility Group Box 2 (HMGB2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMGB2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-HMGB2 Antibody

Binding Specificity: Middle Region

Specificity: This antibody detects HMGB2 at center.

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human HMGB2.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA 1: 1,000. Western blotting 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Target Details for HMGB2

Target: HMGB2 (High Mobility Group Box 2 (HMGB2))

Alternative Name: HMGB2 / HMG2

Background: HMGB2 is a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.Synonyms: High mobility group protein 2, High mobility group protein B2

Gene ID: 3148, 9606

UniProt: P26583

Pathways: Cellular Response to Molecule of Bacterial Origin