CLK2 antibody (N-Term)

Catalog No. ABIN359676

The Rabbit Polyclonal anti-CLK2 antibody (ABIN359676) specifically detects CLK2 in WB and EIA. The antibody is reactive with Human samples.

Quick Overview for CLK2 antibody (N-Term) (ABIN359676)

Target: CLK2 (CDC-Like Kinase 2 (CLK2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLK2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-CLK2 Antibody

Binding Specificity: N-Term

Specificity: This antibody reacts to CLK2.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human CLK2.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Flow cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for CLK2

Target: CLK2 (CDC-Like Kinase 2 (CLK2))

Alternative Name: CLK2

Background: This gene encodes a member of the CLK family of dual specificity protein kinases. CLK family members have shown to interact with, and phosphorylate, serine- and arginine-rich (SR) proteins of the spliceosomal complex, which is a part of the regulatory mechanism that enables the SR proteins to control RNA splicing. This protein kinase is involved in the regulation of several cellular processes and may serve as a link between cell cycle progression, apoptosis, and telomere length regulation.Synonyms: CDC-like kinase 2, CLK-2, Dual specificity protein kinase CLK2

Gene ID: 1196, 9606

UniProt: P49760

Pathways: Regulation of Carbohydrate Metabolic Process