IL17 Receptor B antibody (Extracellular Domain)

Catalog No. ABIN360915

This anti-IL17 Receptor B antibody is a Rat Monoclonal antibody detecting IL17 Receptor B in WB. Suitable for Mouse.

Quick Overview for IL17 Receptor B antibody (Extracellular Domain) (ABIN360915)

Target: IL17 Receptor B (IL17RB) (Interleukin 17 Receptor B (IL17RB))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This IL17 Receptor B antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 9J28

Product Details anti-IL17 Receptor B Antibody

Binding Specificity: Extracellular Domain

Specificity: This antibody detects Mouse IL-17BR. No cross activity with Mouse IL-17R.

Purification: Protein A/G Affinity Chromatography

Immunogen: Recombinant protein of IL-17B R extracellular domain.

Isotype: IgG2

Application Details

Application Notes: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.

Buffer: PBS without stabilizer

Preservative: Without preservative

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for IL17 Receptor B

Target: IL17 Receptor B (IL17RB) (Interleukin 17 Receptor B (IL17RB))

Alternative Name: IL17RB / IL17BR

Background: Recently, a number of cytokines belonging to the interleukin IL17 family have been identified. These are termed as IL17B, IL17C and IL17E. IL17 is a potent proinflammatory cytokine that plays roles in a number of diseases including rheumatoid arthritis, multiple sclerosis, and promotion of tumor growth. IL17B, C, and E like IL17 are able to induce proinflammatory responses. However, they do not bind to the IL17 receptor suggesting that additional IL17R related receptor might exist. Receptor for IL17B and IL17E have been independently isolated and have been designated as EV127 (in mouse) and IL17RH1 (in human), respectively. IL17E induces activation of NFkB pathway and like IL17 also induces production of IL8. IL17RH1 mRNA is highly expressed in Kidney and liver and at moderate level in small intestine, colon, and brain.Synonyms: Cytokine receptor CRL4, EVI27, IL-17 receptor B, IL-17 receptor homolog 1, IL-17RB, Interleukin-17 receptor B, Interleukin-17B receptor

Gene ID: 50905

NCBI Accession: NP_062529

UniProt: Q9JIP3