TREM2 antibody (Extracellular Domain)

Catalog No. ABIN360944

The Rat Monoclonal anti-TREM2 antibody has been validated for WB. It is suitable to detect TREM2 in samples from Mouse.

Quick Overview for TREM2 antibody (Extracellular Domain) (ABIN360944)

Target: TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This TREM2 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 5J46

Product Details anti-TREM2 Antibody

Binding Specificity: Extracellular Domain

Purification: Protein A/G Affinity Chromatography

Sterility: 0.2 μm filtered

Immunogen: Purified Mouse Recombinant TREM-2b extracellular domain

Isotype: IgG2

Application Details

Application Notes: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 200 μL sterile PBS and the final concentration is 0.5 mg/mL.

Buffer: 0.2 μm filtered solution in PBS, None

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody at -20 °C.

Target Details for TREM2

Target: TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))

Alternative Name: TREM2

Background: TREM2 is a single Ig domain receptor expressed by cells of myeloid lineage. Two closely related transcripts were reported in mouse and designated TREM2a and TREM2b. TREM2 is a pattern recognition receptor that binds anionic ligands. It associates with the adapter protein DAP12 to deliver an activating signal that plays a role in both innate and adaptive immune responses.Synonyms: TREM-2b, Triggering receptor expressed on monocytes 2, Triggering receptor expressed on myeloid cells 2

Gene ID: 10090

UniProt: Q99NH8