GlcB (M. Tuberculosis) antibody
Quick Overview for GlcB (M. Tuberculosis) antibody (ABIN361286)
Target
Reactivity
Host
Clonality
Application
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Purpose
- Anti-GlcB (M. tuberculosis) Purified
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Specificity
- The rabbit polyclonal antibody to GlcB reacts with Mycobacterium tuberculosis protein GlcB (malate synthase, Rv1837c).
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Purification
- Purified by ligand affinity chromatography.
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Purity
- > 95 % (by SDS-PAGE)
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Immunogen
- Recombinant GlcB protein (produced in E. coli)
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- Store at 2-8°C. Do not freeze.
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- GlcB (M. Tuberculosis)
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Background
- Malate synthase,The Mycobacterium tuberculosis antigen GlcB (malate synthase) catalyzes synthesis of malate from glyoxylate and acetyl-CoA. This reaction is part of the glyoxylate cycle, which allows the bacterium to derive its carbon requirements from two-carbon compounds by bypassing the two carbocylation steps of the cytric acid cycle. This enzyme is up-regulated in response to phagocytosis and it is a virulence or persistence factor.,Rv1837c
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Gene ID
- 885713
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UniProt
- P9WK17
Target
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