GRIN2C antibody (N-Term)

Catalog No. ABIN361398

Cited in 1 publication. The Rabbit Polyclonal anti-GRIN2C antibody (ABIN361398) specifically detects GRIN2C in ELISA, WB and IP. The antibody is reactive with Rat samples.

Quick Overview for GRIN2C antibody (N-Term) (ABIN361398)

Target: GRIN2C (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRIN2C antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-GRIN2C Antibody

Binding Specificity: N-Term

Specificity: Specific for endogenous levels of the ~140 kDa NR2C subunit of the NMDA receptor. Also labels the ~180 kDa NR2A and the ~180 kDa NR2B subunits of the NMDA receptor. Immunolabeling is blocked by preadsorption of antibody with the immunogen that was used to generate the antibody.

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Our NMDA NR2C Subunit rabbit polyclonal primary antibody is produced in-house. It detects NMDA NR2C Subunit and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB, IP.

Purification: Prepared from pooled rabbit serum by affinity purification using a column to which the fusion protein immunogen was coupled.

Immunogen: Fusion protein from the N-terminal region of the NR2C subunit of the rat NMDA receptor.

Isotype: IgG

Application Details

Application Notes:

Dilution Range: IP: 3 μL per 200 μg lysate

Dilution Range: WB Brain: 1:1000

Dilution Range: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Reconstitute in 50 μl phosphate buffered saline (PBS: 137 mM NaCl, 7.5 mM Na2HPO4, 2.7 mM KCl, 1.5 mM KH2PO4, pH 7.4) before use. After reconstitution it is recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

Expiry Date: 12 months

References for anti-GRIN2C antibody (ABIN361398)

Wang, Imamura, Ishibashi, Chandana, Yamamoto, Noda: "The Reck tumor suppressor protein alleviates tissue damage and promotes functional recovery after transient cerebral ischemia in mice." in: Journal of neurochemistry, (2010) (PubMed).

Target Details for GRIN2C

Target: GRIN2C (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C))

Alternative Name: GRIN2C

Background:

Synonyms: GluN2C antibody, Glutamate [NMDA] receptor subunit epsilon-3 antibody, Glutamate Receptor Ionotropic N Methyl D Aspartate 2C antibody, Glutamate receptor ionotropic NMDA 2C antibody, Glutamate receptor ionotropic N methyl D aspartate 2C antibody, Grin2c antibody, Grin 2c antibody, GRIN2C antibody, GRIN 2C antibody, N Methly D Aspartate Receptor Channel Subunit Epsilon 3 antibody, N Methyl D Aspartate Receptor Subtype 2C antibody, N methyl D aspartate receptor subunit 2C antibody, N-methyl D-aspartate receptor subtype 2C antibody, NMDAR2C antibody, NMDE3_HUMAN antibody, NR2C antibody, OTTHUMP00000041930 antibody

Description Logic: Our NMDA NR2C Subunit rabbit polyclonal primary antibody is produced . It detects NMDA NR2C Subunit and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB, IP.

Gene Name Alternatives: GRIN2C

Molecular Weight: 140 kDa

Gene ID: 24411

UniProt: Q00961

Pathways: Synaptic Membrane