Choline Acetyltransferase antibody
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- Target See all Choline Acetyltransferase (CHAT) Antibodies
- Choline Acetyltransferase (CHAT) (Choline O-Acetyltransferase (CHAT))
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Reactivity
- Human
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Host
- Goat
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Clonality
- Polyclonal
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Conjugate
- This Choline Acetyltransferase antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Specificity
- Specific for the ~ 70k choline acetyltransferase protein
- Cross-Reactivity
- Bird (Avian), Chicken, Guinea Pig, Human, Mouse (Murine), Non-Human Primate
- Purification
- Affinity Purified
- Immunogen
- Native choline acetyltransferase purifed from human placenta
- Top Product
- Discover our top product CHAT Primary Antibody
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anti-Choline O-Acetyltransferase (CHAT) (AA 517-732) antibody
CHAT Reactivity: Human WB, ELISA, ICC, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Choline O-Acetyltransferase (CHAT) (AA 331-630) antibodyCHAT Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Choline O-Acetyltransferase (CHAT) (AA 98-128) antibodyCHAT Reactivity: Human, Mouse WB, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Choline O-Acetyltransferase (CHAT) (AA 354-592) antibodyCHAT Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Choline O-Acetyltransferase (CHAT) (AA 101-200) antibodyCHAT Reactivity: Human, Mouse, Rat, Dog ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Choline O-Acetyltransferase (CHAT) (AA 98-128), (N-Term) antibodyCHAT Reactivity: Human, Mouse WB, IF Host: Rabbit Polyclonal RB18046 unconjugated
anti-Choline O-Acetyltransferase (CHAT) (C-Term) antibodyVerified CHAT Reactivity: Mouse, Rat WB, ELISA, IHC Host: Goat Polyclonal unconjugated
anti-Choline O-Acetyltransferase (CHAT) (AA 446-652) antibodyCHAT Reactivity: Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Choline O-Acetyltransferase (CHAT) (C-Term) antibodyCHAT Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Choline O-Acetyltransferase (CHAT) (N-Term) antibodyCHAT Reactivity: Human WB, IF, ICC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Recommended Dilution: WB: 1:100 IHC: 1:100 Quality Control: Western blots performed on each lot.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 100 μL in 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
- Storage
- -20 °C
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- Target
- Choline Acetyltransferase (CHAT) (Choline O-Acetyltransferase (CHAT))
- Alternative Name
- CHAT (CHAT Products)
- Background
- Choline acetyltransferase is a neuronal enzyme which catalyzes the reaction between Acetyl CoA and choline resulting in the formation of acetylcholine. It is therefore found primarily in cholinergic neurons making it a valuable marker for diseases associated with decreased cholinergic function such as Schizophrenia, Alzheimer disease (AD) and Down syndrome (Holt et al. 1999). Decreased choline acetyltransferase activity in particular has been shown in Schizophrenic subjects (Karson et al 1993). It has furthermore been demonstrated that in patients with AD, there are significantly lower levels of cortical ChAT that correlate with severity of the disease as measured by loss of neuropsychological function (Baskin et al. 1999). Anti-Choline Acetyltransferase Western blot of rat brain lysate showing specific immunolabeling of the ~70k ChAT
- Molecular Weight
- '70 kDa
- Gene ID
- 1103
- Pathways
- Skeletal Muscle Fiber Development
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