GRIPAP1 antibody (C-Term)

Catalog No. ABIN361431

This anti-GRIPAP1 antibody is a Rabbit Polyclonal antibody detecting GRIPAP1 in WB. Suitable for Rat.

Quick Overview for GRIPAP1 antibody (C-Term) (ABIN361431)

Target: GRIPAP1 (GRIP1 Associated Protein 1 (GRIPAP1))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRIPAP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GRIPAP1 Antibody

Binding Specificity: C-Term

Specificity: Specific for the ~95k GRASP protein.

Cross-Reactivity: Mouse (Murine), Rat (Rattus)

Predicted Reactivity: bovine, canine, human

Purification: Antigen Affinity Purified from Pooled Serum

Immunogen: Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH

Application Details

Application Notes: Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Storage: -20 °C

Target Details for GRIPAP1

Target: GRIPAP1 (GRIP1 Associated Protein 1 (GRIPAP1))

Alternative Name: GRIPAP1

Background: PDZ domain-containing proteins, such as PSD-95 and GRIP are thought to play key roles in glutamate receptor plasticity. GRIP-associated proteins (GRASPs) that bind to distinct PDZ domains within GRIP also play key roles in regulation of glutamate receptor function. GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo (Scannevin and Huganir, 2000). Recent work suggests that GRASP-1 may regulate neuronal ras signaling and contribute to the regulation of AMPA receptor distribution by NMDA receptor activity (Ye et al., 2000). Anti-GRASP Western blot of rat cerebellar lysate showing the specific immunolabeling of the ~95k GRASP protein.

Molecular Weight: '95 kDa

Gene ID: 116493

UniProt: Q9JHZ4

Pathways: SARS-CoV-2 Protein Interactome