beta Catenin antibody (AA 31-35)

Catalog No. ABIN362862

The Rabbit Polyclonal anti-beta Catenin antibody has been validated for WB, IHC and IF. It is suitable to detect beta Catenin in samples from Human, Mouse and Rat. There are 3+ publications available.

Quick Overview for beta Catenin antibody (AA 31-35) (ABIN362862)

Target: beta Catenin (CATNB) (Catenin, beta (CATNB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This beta Catenin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-beta Catenin Antibody

Binding Specificity: AA 31-35

Specificity: The antibody detects endogenous level of total b-Catenin protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.

Immunogen: Peptide sequence around AA 31-35 (L-D-S-G-I) derived from Human b-Catenin. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Isotype: IgG

Application Details

Application Notes: Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100
Immunofluorescence: 1:100-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

References for anti-beta Catenin antibody (ABIN362862)

Wang, He, Meng, Liu, Pu, Ji: "A proteomics analysis of rat liver membrane skeletons: the investigation of actin- and cytokeratin-based protein components." in: Journal of proteome research, Vol. 9, Issue 1, pp. 22-9, (2010) (PubMed).

Liao, Wang, Chen, Wang, Wu: "Lipopolysaccharide-induced inhibition of connexin43 gap junction communication in astrocytes is mediated by downregulation of caveolin-3." in: The international journal of biochemistry & cell biology, Vol. 42, Issue 5, pp. 762-70, (2010) (PubMed).

Han, Yang, Yue, Huang, Liu, Pu, Jiang, Yan, Jiang, Kang: "Inactivation of PI3K/AKT signaling inhibits glioma cell growth through modulation of ?-catenin-mediated transcription." in: Brain research, Vol. 1366, pp. 9-17, (2010) (PubMed).

Target Details for beta Catenin

Target: beta Catenin (CATNB) (Catenin, beta (CATNB))

Alternative Name: beta-Catenin

Background: Involved in the regulation of cell adhesion and in signal transduction through the Wnt pathway.

Molecular Weight: 92 kDa

NCBI Accession: NP_001091

UniProt: P35222

Pathways: Peptide Hormone Metabolism