ERK1/2 antibody (AA 202-206)
Quick Overview for ERK1/2 antibody (AA 202-206) (ABIN362912)
Target
See all ERK1/2 (MAPK1/3) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 202-206
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Specificity
- The antibody detects endogenous level of total p44/42 MAP Kinase protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Specificity/Sensitivity p44/42 MAP Kinase (Ab-204) antibody detects endogenous levels of total p44/42 MAP Kinase protein.
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Immunogen
- Peptide sequence around AA 202-206 (T-E-Y-V-A) derived from Human p44, 42 MAP Kinase. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
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Isotype
- IgG
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Application Notes
- Western blotting: 1:500-1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- ERK1/2 (MAPK1/3) (Mitogen-Activated Protein Kinase 1/3 (MAPK1/3))
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Alternative Name
- p44/42 MAP Kinase
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Background
- Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. Phosphorylates EIF4EBP1, required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2).
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Molecular Weight
- 44 kDa
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NCBI Accession
- NP_001035
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UniProt
- P27361
Target
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