AIP antibody
Quick Overview for AIP antibody (ABIN363261)
Target
See all AIP AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- Reacts with human ~38 kDa AIP
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Cross-Reactivity
- Mouse (Murine), Rat (Rattus)
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Cross-Reactivity (Details)
- Cross reacts with mouse and rat protein.
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Purification
- Cell culture supernatant
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Immunogen
- Bacterially expressed human AIP/ARA9.
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Isotype
- IgG1
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Application Notes
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
WB1:1000 ChIP 1:10-1:500 IP1:10-1:100 -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- , Sodium azide 0.1 %
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C/-80 °C
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Storage Comment
- Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
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- AIP (Aryl Hydrocarbon Receptor Interacting Protein (AIP))
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Alternative Name
- AH Receptor-Interacting Protein (AIP)
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Background
- AIP/ARA9 plays a positive role in AHR-mediated signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting. It was originally identified as a negative regulator of hepatitis B virus X-associated protein (hence named XAP2 also) and later was shown as Hsp90-associated protein which specifically interacts with AhR leading to regulation of AhR intracellular localization as well as protein stability via inhibition of AhR ubiquitination.
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Gene ID
- 9049
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UniProt
- O00170
Target
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