Beclin 1 antibody

Catalog No. ABIN363435

This anti-Beclin 1 antibody is a Rabbit Polyclonal antibody detecting Beclin 1 in WB, IF, ICC, IP and IHC (p). Suitable for Human, Mouse and Rat.

Quick Overview for Beclin 1 antibody (ABIN363435)

Target: Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Beclin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Beclin 1 Antibody

Specificity: Reacts with human ~52 kDa Beclin 1 protein

Cross-Reactivity: Mouse (Murine), Rat (Rattus)

Cross-Reactivity (Details): Cross-reacts with mouse and rat protein.

Purification: Antigen affinity purified

Immunogen: Internal synthetic peptide to human Beclin 1, containing residues within 1-100 This sequence has 94% identity with the mouse sequence and 88% identity with the rat sequence

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
ICC/IF: 1:50 - 1:200 IHC - P : 1:400 IP : 1/80 WB : 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.15 mg/mL

Buffer: PBS, Glycerol 30 %, Sodium azide 0.05 %

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze.

Target Details for Beclin 1

Target: Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))

Alternative Name: Beclin-1

Background: Plays a central role in autophagy. Required for the abcission step in cytokinesis. May play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus.

Gene ID: 8678

Pathways: Autophagy