HPV16 E7 antibody

Catalog No. ABIN363828

This anti-HPV16 E7 antibody is a Mouse Monoclonal antibody detecting HPV16 E7 in WB and ELISA. Suitable for Human Papillomavirus (HPV).

Quick Overview for HPV16 E7 antibody (ABIN363828)

Target: HPV16 E7 (HPV-16 E7) (Human Papilloma Virus 16 E7 (HPV-16 E7))

Reactivity: Human Papillomavirus (HPV)

Host: Mouse

Clonality: Monoclonal

Conjugate: This HPV16 E7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 716-F10

Product Details anti-HPV16 E7 Antibody

Specificity: Recognizes both the monomer and dimer forms of the E7 oncoprotein of human papilloma virus 16. Human papillomavirus (HPV) is a diverse group of DNA-based viruses that infect skin and mucous membranes of humans and animals. Some HPV types are the causative agents of cervical cancer, with types 16 and 18 being particularly high-risk. The viral proteins E6 and E7 disrupts normal cell cycle regulation by interacting with p53 (a tumor-suppressing transcription factor) and Rb (retinoblastoma protein, also a tumor-suppressor). E7 particularly binds to Rb and histone deacetylases, resulting in activation of the E2F genes, which code for a family of transcription factors. The viral proteins E6 and E7 might be of particular interest in the development of therapeutic vaccines, since they are expressed early in viral infection. Does not cross-react with E7 protein of HPV-18.

Purification: Affinity purified

Immunogen: Oncoprotein E7 from human papillomavirus 16.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Target Species of Antibody: Human Papillomavirus

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.2, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for HPV16 E7

Target: HPV16 E7 (HPV-16 E7) (Human Papilloma Virus 16 E7 (HPV-16 E7))

Alternative Name: HPV16 E7

Target Type: Viral Protein

Background: Name/Gene ID: HPV16-E7

Synonyms: HPV16-E7

Gene ID: 1489079