CD90 antibody
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- Target See all CD90 (THY1) Antibodies
- CD90 (THY1)
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Reactivity
- Mouse
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Host
- Rat
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Clonality
- Monoclonal
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Conjugate
- This CD90 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)
- Specificity
- This antibody recognises Thy-1.1 and Thy-1.2 alloantigens (Thy-1 epitope region A). MAb G7 stimulates T-cell proliferation and IL-2 secretion, via signalling through the T-cell receptor/CD3 complex. (Ref.1,5-7). It has also been reported to promote apoptosis of thymocytes and CTL clones (Ref.4,7) and to mediate adhesion of thymocytes to thymic stroma. (Ref.8)
- Characteristics
- Synonyms: Thy-1, THY1, CDw90, Thy-1 membrane glycoprotein
- Purification
- Purified
- Clone
- G7
- Isotype
- IgG2c
- Top Product
- Discover our top product THY1 Primary Antibody
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- Application Notes
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Flow Cytometry. (Ref.1,10)Immunohistochemistry (Acetone-Fixed, Frozen Sections). (Ref.10)In vitro T Cell Activation. (Ref.1,5,6,9)Induction of apoptosis.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.
- Storage
- 4 °C/-20 °C
- Storage Comment
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - Expiry Date
- 12 months
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- Target
- CD90 (THY1)
- Alternative Name
- CD90 (THY1 Products)
- Background
- CD90/Thy-1, a GPI-anchored molecule and one of the smallest members of the immunoglobulin superfamily of cell surface receptors, consists of a single V-set domain. (Ref.1-4) It is expressed on thymocytes, peripheral T lymphocytes, some intraepithelial T lymphocytes and neurons of all mouse strains. (Ref.1,2)Synonyms: CDw90, THY1, Thy-1, Thy-1 membrane glycoprotein
- Gene ID
- 21838
- UniProt
- P01831
- Pathways
- Cell-Cell Junction Organization
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