CD79B
Reactivity: Human
FACS
Host: Mouse
Monoclonal
CB3-1
APC
Application Notes
Flow Cytometry. (Ref.1,2)Immunoprecipitation. Immunohistochemistry on Frozen Sections. (Ref.3)Western Blotting. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Concentration
0.5 mg/mL
Buffer
PBS without preservatives.
Preservative
Without preservative
Storage
-20 °C
Storage Comment
Store the antibody undiluted (in aliquots) at -20 °C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Murine CD79 is a 23/21 kDa disulfide-linked heterodimer composed of an alpha chain (CD79a/mb-1) and a beta chain (CD79b/B29) that associates non-covalently with membrane immunoglobulin (Ig) to form the B cell receptor (BCR) complex. Its expression is restricted to B lymphocytes, first appearing on the surface at the pro-B cell stage prior to productive Ig gene rearrangements and remaining through all stages of B-cell differentiation prior to plasma cells. It has been proposed that the CD79 complex on pro-B cell surfaces may function to induce early B-cell differentiation. (Ref.1)Synonyms: B-Cell marker, B-cell antigen receptor complex-associated protein beta-chain, B-cell-specific glycoprotein B29, B29, IGB, Immunoglobulin-associated B29 protein