MHC Class II I-Ab antibody (FITC)
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- Target See all MHC Class II I-Ab products
- MHC Class II I-Ab
- Reactivity
- Mouse
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Host
- Rat
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Clonality
- Monoclonal
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Conjugate
- This MHC Class II I-Ab antibody is conjugated to FITC
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Application
- Flow Cytometry (FACS)
- Characteristics
- Synonyms: H2-Eb1, H-2 class II histocompatibility antigen I-A beta chain
- Clone
- NIMR-4
- Isotype
- IgG2b
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anti-MHC Class II I-Ab antibody
Reactivity: Mouse FACS Host: Mouse Monoclonal 25-9-3 unconjugated
anti-MHC Class II I-Ab antibody (PE)Reactivity: Mouse FACS Host: Mouse Monoclonal 25-9-3 PE
anti-MHC Class II I-Ab antibody (Biotin)Reactivity: Mouse FACS Host: Mouse Monoclonal 25-9-3 Biotin
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- Application Notes
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Flow Cytometry: < / = 1 μg/10^6 cells.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- PBS containing 0.09 % Sodium Azide as preservative.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
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Store the antibody undiluted at 2-8 °C for one month or in (aliquots) at -20 °C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - Expiry Date
- 12 months
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- Target
- MHC Class II I-Ab
- Abstract
- MHC Class II I-Ab Products
- Background
- MHC Class II antigens are heterodimers consisting of one alpha chain(31-34kD) and one beta chain (26-29kD). The family of monoclonal antibodies (ER-TR 3, ER-TR 2, ER-TR 1) detect MHC class II antigens encoded by the murine Ia region of the H-2 complex, corresponding to the human HLA-DR region. MHC Class II antigens are a valuable tool for studying T helper cell interaction with class II positive antigen presenting cells (dendritic cells, B cells, macrophages) and offer new possibilities for studying the development of T helper cells since these antibodies also stain stromal cells in the thymus. MHC Class II antigens are also inducible on a number of other cells (endothelium and epithelial cells) by interferon gamma.Synonyms: H-2 class II histocompatibility antigen I-A beta chain, H2-Eb1
- UniProt
- P18468
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