MHC Class II I-Ab antibody

Catalog No. ABIN371147

The Mouse Monoclonal anti-MHC Class II I-Ab antibody is suitable to detect MHC Class II I-Ab in samples from Mouse. It has been validated for FACS and Func.

Quick Overview for MHC Class II I-Ab antibody (ABIN371147)

Target: MHC Class II I-Ab

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This MHC Class II I-Ab antibody is un-conjugated

Application: Flow Cytometry (FACS), Functional Studies (Func)

Clone: 25-09-03

Product Details anti-MHC Class II I-Ab Antibody

Characteristics: Synonyms: H2-Eb1, H-2 class II histocompatibility antigen I-A beta chain

Purification: Purified

Immunogen: C3H. SW splenocytes. (Ref. 1)

Isotype: IgM

Application Details

Application Notes: Flow Cytometry. Complement-dependent Cytotoxicity Assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for MHC Class II I-Ab

Target: MHC Class II I-Ab

Background: MHC Class II antigens are involved in antigen presentation by Antigen Presenting Cells (APCs) to CD4+ T cells. They are constitutively expressed on APCs including B cells, macrophages, monocytes and dendritic cells, and are inducible on a number of other cells (endothelium and epithelial cells) by interferon gamma. The Mouse H2 Ab locus is orthologous to human DQB, which varies from typical class II genes in that both the alpha and beta chains are polymorphic.Synonyms: H-2 class II histocompatibility antigen I-A beta chain, H2-Eb1

UniProt: P18468