ICAM2 antibody

Catalog No. ABIN371207

The Rat Monoclonal anti-ICAM2 antibody has been validated for FACS, IP, IHC (fro) and Func. It is suitable to detect ICAM2 in samples from Mouse.

Quick Overview for ICAM2 antibody (ABIN371207)

Target: ICAM2 (Intercellular Adhesion Molecule 2 (ICAM2))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This ICAM2 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Clone: 3C4

Product Details anti-ICAM2 Antibody

Specificity: This antibody is specific to ICAM-2 (CD102). It blocks the interaction between ICAM-2 and LFA-1. (Ref.1)

Characteristics: Synonyms: ICAM-2, Intercellular adhesion molecule 2

Purification: Purified

Immunogen: COS cells transfected with mouse ICAM-2 cDNA. (Ref. 1)

Isotype: IgG2a

Application Details

Application Notes: Flow Cytometry: < / = 1 μg/10^6 cells. (Ref.1,2)Immunohistochemistry on Frozen Sections. (Ref.3)Immunoprecipitation. In vitro blocking assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for ICAM2

Target: ICAM2 (Intercellular Adhesion Molecule 2 (ICAM2))

Alternative Name: CD102 / ICAM2

Background: ICAM2 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin like C2 type domains, and bind to the leukocyte adhesion LFA1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA1 dependent cell adhesion. It mediates adhesive interactions important for antigen specific immune response, NK cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.Synonyms: ICAM-2, Intercellular adhesion molecule 2

Gene ID: 15896

UniProt: P35330