TOLLIP antibody
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- Target See all TOLLIP Antibodies
- TOLLIP (Toll Interacting Protein (TOLLIP))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This TOLLIP antibody is un-conjugated
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA), Flow Cytometry (FACS)
- Specificity
- This antibody is specific to Human Tollip. Does not react to TLR2, TLR4, TLR6, TLR7, TLR8 and TLR10 recombinant proteins.
- Characteristics
- Synonyms: Toll-interacting protein
- Purification
- Purified
- Immunogen
- Recombinant Tollip.
- Clone
- SB40a
- Isotype
- IgG2a
- Top Product
- Discover our top product TOLLIP Primary Antibody
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anti-Toll Interacting Protein (TOLLIP) (AA 1-274) antibody
TOLLIP Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Toll Interacting Protein (TOLLIP) (AA 1-274) antibodyTOLLIP Reactivity: Human WB, ELISA, IP Host: Mouse Monoclonal 1A5-2A3 unconjugated
anti-Toll Interacting Protein (TOLLIP) (AA 19-254) antibodyTOLLIP Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Toll Interacting Protein (TOLLIP) (AA 221-250), (C-Term) antibodyTOLLIP Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB4409 unconjugated
anti-Toll Interacting Protein (TOLLIP) (AA 1-274) antibodyTOLLIP Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-Toll Interacting Protein (TOLLIP) (AA 1-274) antibodyTOLLIP Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-Toll Interacting Protein (TOLLIP) (AA 28-261) antibodyTOLLIP Reactivity: Human WB, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-Toll Interacting Protein (TOLLIP) (AA 86-163) antibodyTOLLIP Reactivity: Human IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Toll Interacting Protein (TOLLIP) (N-Term) antibodyTOLLIP Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Monkey, Guinea Pig, Horse, Rabbit, Dog, Hamster WB Host: Rabbit Polyclonal unconjugated
anti-Toll Interacting Protein (TOLLIP) (AA 61-274) antibodyTOLLIP Reactivity: Human WB, ELISA Host: Mouse Monoclonal k1B17 unconjugated
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- Application Notes
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ELISA. Western Blot. Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- 100 mM Borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added.
- Storage
- 4 °C/-20 °C
- Storage Comment
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - Expiry Date
- 12 months
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- Target
- TOLLIP (Toll Interacting Protein (TOLLIP))
- Alternative Name
- TOLLIP (TOLLIP Products)
- Background
- Toll like protein is a component of the signaling pathway of IL1 and Toll like receptors. It inhibits cell activation by microbial products. Tollip recruits IRAK1 to the IL1 receptor complex and inhibits IRAK1 phosphorylation and kinase activity. It oligomerizes and binds to TLR2 and the TLR4-MD2 complex via its C terminus. It exists as a complex with IRAK1 in unstimulated cells. Upon IL1 signaling, Tollip binds to the activated IL1 receptor complex containing IL-1RI, IL-1RacP and the adapter protein MyD88, where it interacts with the TIR domain of IL-1RacP. MyD88 then triggers IRAK1 autophosphorylation, which in turn leads to the dissociation of IRAK1 from Tollip and IL-1RAcP.Synonyms: Toll-interacting protein
- Gene ID
- 54472
- UniProt
- Q9H0E2
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