AMPD1 antibody (AA 140-190)

Catalog No. ABIN372277

This Rabbit Polyclonal antibody specifically detects AMPD1 in WB and IHC (p). It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Monkey, Zebrafish (Danio rerio) and Chimpanzee.

Quick Overview for AMPD1 antibody (AA 140-190) (ABIN372277)

Target: AMPD1 (Adenosine Monophosphate Deaminase 1 (AMPD1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Monkey, Zebrafish (Danio rerio), Chimpanzee

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AMPD1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-AMPD1 Antibody

Binding Specificity: AA 140-190

Specificity: This antibody recognizes AMPD1.

Cross-Reactivity (Details): Species reactivity (expected):Bovine, Chimpanzee, Dog (Canine), Monkey, Mouse, Rat and Zebrafish.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide corresponding to a portion of the amino acids 140-190 of Human AMPD1.

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry on Paraffin Sections: 10 μg/mL. Western Blot: 0.5-2.0 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % Sodium Azide as preservative and 0.2 % Gelatin as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for AMPD1

Target: AMPD1 (Adenosine Monophosphate Deaminase 1 (AMPD1))

Alternative Name: AMP Deaminase 1 / AMPD1

Background: AMP deaminase (AMPD) is an allosteric enzyme that plays a critical role in energy metabolism. There are three functional isoforms of AMPD. AMPD1 is the skeletal muscle-specific isoform M located in type II muscle fibers, neuromuscular junctions and in capillaries. Defects in AMPD1 are the cause of adenosine monophosphate deaminase deficiency muscle type (AMPDDM). AMPDDM is a metabolic disorder resulting in exercise-related myopathy. It is characterized by exercise-induced muscle aches, cramps, and early fatigue.Synonyms: AMP deaminase isoform M, Myoadenylate deaminase

Molecular Weight: 87 kDa.

Gene ID: 270

NCBI Accession: NP_000027

UniProt: P23109