AMPD1 antibody (AA 230-310)

Catalog No. ABIN7221078

The Rabbit Polyclonal anti-AMPD1 antibody is suitable to detect AMPD1 in samples from Human, Mouse and Rat. It has been validated for ELISA, IHC and IF.

Quick Overview for AMPD1 antibody (AA 230-310) (ABIN7221078)

Target: AMPD1 (Adenosine Monophosphate Deaminase 1 (AMPD1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AMPD1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-AMPD1 Antibody

Binding Specificity: AA 230-310

Purpose: Rabbit Anti-AMPD1 Polyclonal Antibody

Specificity: AMPD1 Polyclonal Antibody detects endogenous levels of AMPD1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human AMPD1 at AA range: 230-310

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for AMPD1

Target: AMPD1 (Adenosine Monophosphate Deaminase 1 (AMPD1))

Alternative Name: AMPD1

Background: AMPD1, AMP deaminase 1, AMP deaminase isoform M, Myoadenylate deaminaseAdenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

Gene ID: 270

UniProt: P23109