Apolipoprotein D antibody (N-Term)

Catalog No. ABIN372486

This anti-Apolipoprotein D antibody is a Rabbit Polyclonal antibody detecting Apolipoprotein D in WB and IHC (p). Suitable for Human, Mouse and Rat.

Quick Overview for Apolipoprotein D antibody (N-Term) (ABIN372486)

Target: Apolipoprotein D (APOD)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Apolipoprotein D antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Apolipoprotein D Antibody

Binding Specificity: N-Term

Specificity: This antibody recognizes Apolipoprotein D (APOD).

Cross-Reactivity (Details): Species reactivity (expected):Human and Rat.
Species reactivity (tested):Mouse.

Purification: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide corresponding to N-terminal residues of mouse APOD.

Isotype: IgG

Application Details

Application Notes: Western Blot: 1 μg/mLImmunohistochemistry on Paraffin Sections: 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: PBS containing 0.01 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for Apolipoprotein D

Target: Apolipoprotein D (APOD)

Alternative Name: Apolipoprotein D (Apo D)

Background: Apolipoprotein D (APO D), a glycoprotein involved in the human plasma lipid transport system. It is a progesterone binding glycoprotein of 24,000 dalton monomer molecular size, is a constituent of high density lipoprotein in plasma. The function of apolipoprotein D in the metabolism of plasma lipoproteins is unclear but the observation that this protein forms complexes with lecithin: cholesterol acyltransferase has led to the suggestion that apolipoprotein D may be involved in cholesterol esterification and transport of substrates and products of the reaction. Apolipoprotein D is expressed in a range of normal tissues including axillary apocrine glands, adrenal cortex and corpus luteum. Peripheral nerves, pituitary, testis, cerebellum and renal tubes are also positive. APO D was first isolated in large quantity as GCDFP 24, the major protein component of most human breast cyst fluids. In recent studies, Apo D immunoreactivity has been shown to be an early indicator of prostate cancer and advanced primary prostate tumors.Synonyms: APOD, Apo-D

Molecular Weight: 21 kDa.

Gene ID: 347

NCBI Accession: NP_001638

UniProt: P05090

Pathways: Platelet-derived growth Factor Receptor Signaling