RTEL1 antibody (N-Term)

Catalog No. ABIN372518

The Rabbit Polyclonal anti-RTEL1 antibody is suitable to detect RTEL1 in samples from Human and Mouse. It has been validated for WB, IHC (p) and EIA.

Quick Overview for RTEL1 antibody (N-Term) (ABIN372518)

Target: RTEL1 (Regulator of Telomere Elongation Helicase 1 (RTEL1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RTEL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-RTEL1 Antibody

Binding Specificity: N-Term

Specificity: This antibody recognizes Helicase-Like Protein NHL (RTEL1).

Cross-Reactivity (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide corresponding to N-terminal residues of human RTEL1.

Isotype: IgG

Application Details

Application Notes: ELISA: 1 μg/mLWestern blot: 1 μg/mL. Immunohistochemistry on Paraffin Sections: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.01 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for RTEL1

Target: RTEL1 (Regulator of Telomere Elongation Helicase 1 (RTEL1))

Alternative Name: RTEL1

Background: RTEL1 (Regulator of telomere elongation helicase 1) is probably an ATP-dependent DNA helicase. RTEL1 is a member of the stathmin family, and is related to RAD3/ERCC2, a plasma membrane Ras-related GTPase. The amplification or overexpression of this gene may contribute to cell growth and tumor progression. It is located in a gene-rich cluster on chromosome 20, with other potentially tumor-related genes, such as TNFRSF6B.Synonyms: C20orf41, KIAA1088, NHL, Novel helicase-like, Regulator of telomere elongation helicase 1

Molecular Weight: 134 kDa.

Gene ID: 51750

NCBI Accession: NP_057518

UniProt: Q9NZ71