Dynamin 1 antibody (N-Term)

Catalog No. ABIN372615

The Rabbit Polyclonal anti-Dynamin 1 antibody (ABIN372615) specifically detects Dynamin 1 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Chicken and Non-Human Primate samples.

Quick Overview for Dynamin 1 antibody (N-Term) (ABIN372615)

Target: Dynamin 1 (DNM1)

Reactivity: Human, Mouse, Rat, Cow, Chicken, Non-Human Primate

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dynamin 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Dynamin 1 Antibody

Binding Specificity: N-Term

Specificity: Recognizes the ~95k Dynamin protein.

Cross-Reactivity (Details): Species reactivity (expected):Human, Mouse, Bovine (Cow), Chicken and non-Human Primates.
Species reactivity (tested):Rat.

Purification: Affinity Chromatography.

Immunogen: Peptide corresponding to amino acid residues from the N-terminal region of human Dynamin, conjugated to keyhole limpet hemocyanin (KLH).

Isotype: IgG

Application Details

Application Notes: Western Blot: 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody undiluted (in aliquots) at-20 °C.

Target Details for Dynamin 1

Target: Dynamin 1 (DNM1)

Alternative Name: Dynamin-1

Background: Dynamin is a member of a group of nerve terminal proteins called dephosphins that regulate synaptic vesicle endocytosis (Cousin et al., 2001, Graham et al., 2002, Tsuboi et al., 2002). There are 3 known isofoms of Dynamin, each having several splice variants as well. Dynamin I is expressed only in neurons whereas Dynamin II is ubiquitously expressed and Dynamin III is found primarily in the testes. Dynamin 1 is phosphorylated by PKC and dephosphorylated by calcineurin.Synonyms: DNM, DNM1

Gene ID: 140694

NCBI Accession: NP_542420

UniProt: P21575

Pathways: Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling