IL27 antibody (N-Term)

Catalog No. ABIN372855

This anti-IL27 antibody is a Rabbit Polyclonal antibody detecting IL27 in WB, IHC (p) and IF. Suitable for Human and Mouse.

Quick Overview for IL27 antibody (N-Term) (ABIN372855)

Target: IL27 (Interleukin-27 Subunit alpha (IL27))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL27 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Product Details anti-IL27 Antibody

Binding Specificity: N-Term

Specificity: This antibody recognizes Interleukin 27 (IL27).

Cross-Reactivity (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography

Immunogen: Synthetic peptide from Human IL27

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry on paraffin sections: 5 μg/mL. Immunocytochemistry. Western blot: 2 - 4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS, 0.02 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for IL27

Target: IL27 (Interleukin-27 Subunit alpha (IL27))

Alternative Name: Interleukin-27 / IL27A

Background: IL27 is a recently discovered member of the IL6/IL12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the p40-related protein EBI3 and an IL12 p35-related protein termed p28. IL27 is produced after activation by antigen-presenting cells and induces proliferation of naive but not memory CD4+ T-cells. It acts by binding to its receptor WSX-1 and gp130 which results in the activation of a Jak/STAT signaling cascade, suggesting the IL27 is involved in the regulation of immune processes.Synonyms: IL-27 subunit alpha, IL-30, IL27-A, IL30, Interleukin-30, p28

Gene ID: 246778

NCBI Accession: NP_663634

UniProt: Q8NEV9