HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2) (N-Term) antibody

Catalog No. ABIN374419

This Goat Polyclonal antibody specifically detects HIV-1 Tat Interactive Protein 2, 30kDa in WB. It exhibits reactivity toward Human.

Quick Overview for HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2) (N-Term) antibody (ABIN374419)

Target: HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2)

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Product Details

Binding Specificity: N-Term

Specificity: This antibody detects HTATIP2 at N-term.

Purification: Affinity chromatography

Immunogen: Peptide with sequence AETEALSKLREDFR-C, from the N Terminus of the protein sequence Genename: HTATIP2

Application Details

Application Notes: Peptide ELISA: 1/32000. Western blot: 0,3 - 1,0 μg/mL. Approx 30 kDa band observed in Hela and Human Lunglysates (predicted MW of 27.0 kDa according to NP_006401).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details

Target: HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2)

Alternative Name: HTATIP2

Target Type: Viral Protein

Background: TIP30 is a member of the short-chain dehydrogenases/reductases (SDR) family. It is a serine/threonine kinase that phosphorylates the C-terminal domain (CTD) of the largest RNA polymerase II subunit and induces the expression of apoptosis related genes Bad and Siva, as well as metastasis suppressor NM23 H2. It also interacts with an estrogen receptor alpha-interacting coactivator CIA and regulates ERalpha-mediated c-myc transcription. This protein is also known to bind the activation domain of HIV-1 Tat.Synonyms: 30 kDa HIV-1 TAT-interacting protein, CC3, HIV-1 TAT-interactive protein 2, Oxidoreductase HTATIP2, TIP30

Gene ID: 10553

NCBI Accession: NP_001091990

UniProt: Q9BUP3