SCARF1 antibody (Internal Region)

Catalog No. ABIN374467

This Goat Polyclonal antibody specifically detects SCARF1 in WB, IF and EIA. It exhibits reactivity toward Human.

Quick Overview for SCARF1 antibody (Internal Region) (ABIN374467)

Target: SCARF1 (Acetyl LDL Receptor (SCARF1))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This SCARF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Product Details anti-SCARF1 Antibody

Binding Specificity: Internal Region

Sequence: SELDPKGQHV C

Specificity: This antibody is expected to recognize all reported isoforms of SCARF1. Epitope Epitope corresponding to aa 20-31, mapping to the mature Human SCARF1/SREC1 protein.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_003684.2, NP_663325.1, NP_663327.2. Genename: SCARF1

Application Details

Application Notes: Peptide ELISA: 1/64000. Western blot: 0.3 - 1.0 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide and 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SCARF1

Target: SCARF1 (Acetyl LDL Receptor (SCARF1))

Alternative Name: SCARF1

Background: SCARF1 is a scavenger receptor that is expressed in endothelial cells and mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). Transcription factors ZNF444/EZF-2 and SP1 are responsible for the regulation of this gene. Five alternatively spliced transcript variants encoding distinct isoforms have been described.Synonyms: Acetyl LDL receptor, Endothelial cells scavenger receptor, KIAA0149, SREC, Scavenger receptor class F member 1

Gene ID: 8578

NCBI Accession: NP_003684

UniProt: Q14162