HADH antibody (Internal Region)

Catalog No. ABIN374901

The Goat Polyclonal anti-HADH antibody (ABIN374901) specifically detects HADH in WB. The antibody is reactive with Human, Mouse, Rat and Dog samples.

Quick Overview for HADH antibody (Internal Region) (ABIN374901)

Target: HADH (Hydroxyacyl-CoA Dehydrogenase (HADH))

Reactivity: Human, Mouse, Rat, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This HADH antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HADH Antibody

Binding Specificity: Internal Region

Sequence: C-YERGDASKED ID

Specificity: This antibody recognizes HADH / HADHSC.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Canine.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_005318.2

Application Details

Application Notes: Peptide ELISA: 1/64000. Western Blot: 0.01 - 0.03 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for HADH

Target: HADH (Hydroxyacyl-CoA Dehydrogenase (HADH))

Alternative Name: HADH / HCDH

Background: HADHSC functions in the mitochondrial matrix to catalyze the oxidation of straight-chain 3-hydroxyacyl-CoAs as part of the beta-oxidation pathway. Its enzymatic activity is highest with medium-chain-length fatty acids. Mutations in this gene cause one form of familial hyperinsulinemic hypoglycemia. The human genome contains a related pseudogene.Synonyms: HAD, HADHSC, Hydroxyacyl-coenzyme A dehydrogenase mitochondrial, Medium and short chain L-3-hydroxyacyl-coenzyme A dehydrogenase, SCHAD, Short chain 3-hydroxyacyl-CoA dehydrogenase

Gene ID: 3033, 9606

UniProt: Q16836

Pathways: Negative Regulation of Hormone Secretion, Monocarboxylic Acid Catabolic Process