IDS antibody (Internal Region)

Catalog No. ABIN375037

Product Details anti-IDS Antibody

Target: IDS (Iduronate 2-Sulfatase (IDS))

Binding Specificity: Internal Region

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This IDS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Sequence: C-KHFRFRDLEE DP

Specificity: This antibody is expected to recognize isoform a of IDS (NP_000193.1).

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the internal region of Human IDS (NP_000193.1). Genename: IDS

Application Details

Application Notes: Peptide ELISA: 1/16000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for IDS

Target: IDS (Iduronate 2-Sulfatase (IDS))

Alternative Name: IDS / SIDS (IDS Products)

Synonyms: mps2 antibody, sids antibody, zgc:158245 antibody, MPS2 antibody, SIDS antibody, AW214631 antibody, iduronate 2-sulfatase antibody, IDS antibody, CpipJ_CPIJ004938 antibody, ids antibody, Ids antibody

Background: Iduronate 2 sulfatase (IDS) is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Defects in IDS are the cause of mucopolysaccharidosis type II (MPS-II) also known as Hunter syndrome. There are two named isoforms.Synonyms: Alpha-L-iduronate sulfate sulfatase, Iduronate 2-sulfatase, Idursulfase

Gene ID: 3423

NCBI Accession: NP_000193

UniProt: P22304

Pathways: Glycosaminoglycan Metabolic Process